Ornitz Biographical Sketch

Education:

  • University of CA, Davis B.S. 1981 Biochemistry
  • University of WA, Seattle Ph.D. 1987 Biochemistry
  • University of WA, Seattle M.D. 1988 Medicine
  • Harvard Medical School Postdoc 1988-92 Genetics

Scholarships and Awards:

  • American Heart Association Established Investigator Award
  • Arnold and Mabel Beckman Young Investigators Award
  • Lucille Markey Award
  • Medical Scientist Training Program
  • American Heart Association Student Research Associates Program

Research Experience:

  • 7/00-present Professor, Department of Molecular Biology and Pharmacology, Washington University School of Medicine.
  • 11/96-6/00 Associate Professor, Department of Molecular Biology and Pharmacology, Washington University School of Medicine
  • 5/92-10/96 Assistant Professor, Department of Molecular Biology and Pharmacology, Washington University School of Medicine
  • 7/88-4/92 Postdoctoral Fellow with Dr. Philip Leder, Department of Genetics, Harvard Medical School

    Development of a yeast GAL4/UAS binary genetic system to regulate transgene expression in mice. Expression of the int-2 gene in the mammary gland and prostate of transgenic mice. Int-2 and bFGF signal transduction. Biochemical analysis of bFGF/FGF receptor binding interactions. Cloning of a novel tyrosine kinase FGF receptor. Deregulated expression of leukemia inhibitory factor in T cells of transgenic mice. Transactivation of HTLV-I/LTR-myc fusion genes by the HTLV-I-tax gene in transgenic mice.

  • 7/83-3/87 Ph.D. thesis research with Dr. Richard Palmiter, Department of Biochemistry, University of Washington

    • The regulation of tissue-specific gene expression in the pancreas and liver of transgenic mice and the directed oncogenesis of the mouse pancreas by elastase-SV40 T antigen and elastase-H-ras fusion genes.

  • 1/80-6/81 Undergraduate research with Dr. Irwin H. Segel, Dept. of Biochemistry, University of CA, Davis

    • The kinetic mechanism of the enzyme Nitrate Reductase.

  • 1/79-12/79 Undergraduate research with Dr. Don Bergstrom, Department of Chemistry, University of CA, Davis

    • Synthetic organic chemistry of nucleosides.

  • 1/77-8/79 American Heart Association Student Research Associates Program with Dr. George Popjak, Department of Biological Chemistry, UCLA

    • Enzymology of cholesterol biosynthesis.