Related publications:

Hughes, I., Binkley, J., Hurle, B., Green, E.D., Program, N.C.S., Sidow, A., and Ornitz, D.M. (2008). Identification of the Otopetrin Domain, a conserved domain in vertebrate otopetrins and invertebrate otopetrin-like family members. BMC evol biol, in press.

Hughes, I., Blasiole, B., Huss, D., Warchol, M.E., Rath, N.P., Hurle, B., Ignatova, E., Dickman, J.D., Thalmann, R., Levenson, R., et al. (2004). Otopetrin 1 is required for otolith formation in the zebrafish Danio rerio. Dev Biol 276, 391-402.

Hughes, I., Saito, M., Schlesinger, P.H., and Ornitz, D.M. (2007). Otopetrin1 activation by purinergic nucleotides regulates intracellular calcium. Proc Natl Acad Sci U S A 104, 12023-12028.

Hurle, B., Ignatova, E., Massironi, S.M., Mashimo, T., Rios, X., Thalmann, I., Thalmann, R., and Ornitz, D.M. (2003). Non-syndromic vestibular disorder with otoconial agenesis in tilted/mergulhador mice caused by mutations in otopetrin 1. Hum Mol Genet 12, 777-789.

Hurle, B., Ignatova, E., S.E., M., Mashimo, T., Rios, X., Thalmann, I., Thalmann, R., and Ornitz, D.M. (2002). Otoconial agenesis in Tilted and Mergulhador Caused by Mutations in Otopetrin 1 (St. Louis, MO).

Hurle, B., Lane, K., Kenney, J., Tarantino, L.M., Bucan, M., Brownstein, B.H., and Ornitz, D.M. (2001). Physical mapping of the mouse tilted locus identifies an association between human deafness loci DFNA6/14 and vestibular system development. Genomics 77, 189-199.

Ornitz, D.M., Bohne, B.A., Thalmann, I., Harding, G.W., and Thalmann, R. (1998). Otoconial agenesis in tilted mutant mice. Hearing Res 122, 60-70.

Ying, H.C., Hurle, B., Wang, Y., Bohne, B.A., Wuerffel, M.K., and Ornitz, D.M. (1999). High-resolution mapping of tlt, a mouse mutant lacking otoconia. Mamm Genome 10, 544-548.

Ignatova, E.G., Thalmann, I., Xu, B., Ornitz, D.M., and Thalmann, R. (2004). Molecular mechanisms underlying ectopic otoconia-like particles in the endolymphatic sac of embryonic mice. Hear Res 194, 65-72.

Thalmann, I., Hughes, I., Tong, B.D., Ornitz, D.M., and Thalmann, R. (2006). Microscale analysis of proteins in inner ear tissues and fluids with emphasis on endolymphatic sac, otoconia, and organ of Corti. Electrophoresis 27, 1598-1608.

Thalmann, R., Ignatova, E., Kachar, B., Ornitz, D.M., and Thalmann, I. (2001). Development and maintenance of otoconia: biochemical considerations. Ann N Y Acad Sci 942, 162-178.

Wang, Y., Kowalski, P.E., Thalmann, I., Ornitz, D.M., Mager, D.L., and Thalmann, R. (1998). Otoconin-90, the mammalian otoconial matrix protein contains two domains of homology to secretory phospholipase A2. Proc Natl Acad Sci, USA 95, 15345-15350.

Wang, Y., Thalmann, I., Thalmann, R., and Ornitz, D.M. (1999). Mapping the mouse otoconin-90 (Oc90) gene to chromosome 15. Genomics 58, 214-215.