Related publications:
Colvin, J.S., Bohne, B.A., Harding, G.W., McEwen, D.G., and Ornitz, D.M. (1996). Skeletal overgrowth and deafness in mice lacking fibroblast growth factorreceptor 3. Nat Genet 12, 390-397.
Naski, M.C., Colvin, J.S., Coffin, J.D., and Ornitz, D.M. (1998). Repression of hedgehog signaling and BMP4 expression in growth plate cartilage by fibroblast growth factor receptor 3. Development 125, 4977-4988.
Naski, M.C., and Ornitz, D.M. (1998). FGF signaling in skeletal development. Front Biosci 3, D781-794.
Ornitz, D.M. (2001). Regulation of chondrocyte growth and differentiation by fibroblast growth factor receptor 3. Novartis Found Symp 232, 63-76; discussion 76-80, 272-282.
Wang, Q., Green, R.P., Zhao, G., and Ornitz, D.M. (2001). Differential regulation of endochondral bone growth and joint development by FGFR1 and FGFR3 tyrosine kinase domains. Development 128, 3867-3876.
Liu, Z., Xu, J., Colvin, J.S., and Ornitz, D.M. (2002). Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18. Genes Dev 16, 859-869.
Ornitz, D.M., and Marie, P.J. (2002). FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease. Genes Dev 16, 1446-1465.
Yu, K., Xu, J., Liu, Z., Sosic, D., Shao, J., Olson, E.N., Towler, D.A., and Ornitz, D.M. (2003). Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth. Development 130, 3063-3074.
Ornitz, D.M. (2005). FGF signaling in the developing endochondral skeleton. Cytokine Growth Factor Rev 16, 205-213.
Jacob, A.L., Smith, C., Partanen, J., and Ornitz, D.M. (2006). Fibroblast growth factor receptor 1 signaling in the osteo-chondrogenic cell lineage regulates sequential steps of osteoblast maturation. Dev Biol 296, 315-328.
Perlyn, C.A., Morriss-Kay, G., Darvann, T., Tenenbaum, M., and Ornitz, D.M. (2006). A model for the pharmacological treatment of crouzon syndrome.
Neurosurgery 59, 210-215; discussion 210-215.
Hung, I.H., Yu, K., Lavine, K.J., and Ornitz, D.M. (2007). FGF9 regulates early hypertrophic chondrocyte differentiation and skeletal vascularization in the developing stylopod. Dev Biol 307, 300-313.
Yu, K., and Ornitz, D.M. (2008). FGF signaling regulates mesenchymal differentiation and skeletal patterning along the limb bud proximodistal axis. Development 135, 483-491. |